Nonsmokers exposed to secondhand cigarette smoke are at increased risk of chronic kidney disease (CKD), according to new study findings published in the Clinical Journal of the American Society of Nephrology.
The study included 131,196 never-smokers with normal kidney function who participated in the Korean Genome and Epidemiology Study from 2001 to 2014 (mean age 53 years; 75% women). Investigators classified patients into 3 groups based on the frequency of secondhand smoke exposure: no exposure, less than 3 days per week, and 3 or more days per week. In these groups, 1.8%, 1.7%, and 2.0%, respectively, had CKD. Individuals with less than 3 days and 3 days or more of exposure had significant 72% and 44% greater odds of prevalent CKD than the no-exposure group, Jong Hyun Jhee, MD, of Inha University in Korea, and colleagues reported.
The investigators also examined the risk of incident CKD development in a longitudinal cohort of 1948 participants without CKD at baseline. The individuals were a subset of the main cohort.
CKD developed in 319 participants over a mean follow-up period of 104 months. On multivariable analysis, individuals with less than 3 days and 3 days or more of exposure to secondhand smoke had significant 59% and 66% greater odds of CKD, respectively, compared with the no-exposure group.
Secondhand smoke increases CKD risk to a comparable degree as firsthand smoke, according to the researchers.
“These findings suggest that the association of CKD with secondhand smoke exposure could be at least similar to its relationship with active smoking,” Dr Jhee’s team stated. “Although active smoking is an intermittent activity, nonsmokers are commonly exposed to secondhand smoke from multiple smokers. Therefore, some nonsmokers exposed to secondhand smoke could be exposed to a similar dose of cigarette smoke to active smokers.”
With respect to possible mechanisms, smoke may inflame the lungs and spur oxidative stress, ultimately affecting the entire circulation, including the kidneys, the team said. They also cited a recent study suggesting nicotine may cause apoptosis of podocytes.
Reference
Jhee JH, Joo YS, Kee YK, et al. Secondhand smoke and CKD. Clin J Am Soc Nephrol. March 2019, CJN.09540818; DOI:10.2215/CJN.09540818
https://cjasn.asnjournals.org/content/early/2019/03/06/CJN.09540818
There are some natural remedies that can be used in the prevention and eliminate diabetes totally. However, the single most important aspect of a diabetes control plan is adopting a wholesome life style Inner Peace, Nutritious and Healthy Diet, and Regular Physical Exercise. A state of inner peace and self-contentment is essential to enjoying a good physical health and over all well-being. The inner peace and self contentment is a just a state of mind.People with diabetes diseases often use complementary and alternative medicine. I diagnosed diabetes in 2010. Was at work feeling unusually tired and sleepy. I borrowed a cyclometer from a co-worker and tested at 760. Went immediately to my doctor and he gave me prescription like: Insulin ,Sulfonamides,Thiazolidinediones but Could not get the cure rather to reduce the pain but brink back the pain again. i found a woman testimony name Comfort online how Dr Akhigbe cure her HIV and I also contacted the doctor and after I took his medication as instructed, I am now completely free from diabetes by doctor Akhigbe herbal medicine.So diabetes patients reading this testimony to contact his email drrealakhigbe@gmail.com or his Number +2348142454860 He also use his herbal herbs to diseases like:SPIDER BITE, SCHIZOPHRENIA, LUPUS,EXTERNAL INFECTION, COMMON COLD, JOINT PAIN, EPILEPSY,STROKE,TUBERCULOSIS ,STOMACH DISEASE. ECZEMA, PROGENITOR, EATING DISORDER, LOWER RESPIRATORY INFECTION, DIABETICS,HERPES,HIV/AIDS, ;ALS, CANCER , MENINGITIS,HEPATITIS A AND B,ASTHMA, HEART DISEASE, CHRONIC DISEASE. NAUSEA VOMITING OR DIARRHEA,KIDNEY DISEASE. HEARING LOSSDr Akhigbe is a good man and he heal any body that come to him. here is email drrealakhigbe@gmail.com and his Number +2349010754824
ReplyDelete